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However, although their experimental procedure has the potential to act as a low-cost, real-time ultrasensitive assay capable of measuring impedance patterns for point-of-care diagnostics of ME/CFS, the nanoelectronic assay was not developed for routine use and requires further instrumentational development to be deployed for clinical application

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therefore, diagnosis is primarily clinical, although it may be aided by validated questionnaires, neurophysiological examination, as well as imaging studies [10]