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With a short half-life, OH does not travel far, but has a much higher oxidant potential than all the other ROS [12, 20]

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Although to date Aro10 has not been found to be stabilized upon deletion of any known GID E3 ligase substrate receptors 35,37 , our data reveal a correlation with Gid4-dependent regulation, and raise the possibility of yet additional forms of GID E3 ligase regulation to be discovered in future studies

Diabetes 69 , 749759 (2020)