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In addition, it is one of the major conserved pathways of aging that regulate lifespan in model organisms across a great evolutionary distance from Caenorhabditis elegans ( Drosophila (Tatar et al., 2001), and to mice

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Ming X, Brimacombe M, Chaaban J, Zimmerman-Bier B, Wagner GC (2008) Autism spectrum disorders: concurrent clinical disorders

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504 Closely following the global progression toward more sedentary lifestyles and unhealthy diets, the incidence of T2D is increasing and poses a formidable challenge to public health