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Description
methionine, taurine Peptide conjugation: requires glycine and taurine Glucuronidation: requires glucuronic acid, a substance made in the liver Acetylation: requires acetic acid Methylation: requires methylating factors such as folate, B6 and B12 Ideally, phase II acts on the reactive intermediaries as quickly as possible, reducing the time available for them to damage cell membranes and DNA

NAC is known to reach peak plasma levels quickly [11], with a half-life reported to range between 11 min and 6 h, depending on the animal and route of administration [12,13]

Neuron 15 , 711720 (1995)

This process results in suppressed levels of NADPH, which in turn leads to an increase in ROS concentrations

Aging 35, 431441

Retention time and spectral identity confirmed through chromatographic analysis
