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Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist

Consequently, while NAD + precursors or inhibitors of NAD + -consuming enzymes demonstrate therapeutic potential in both conditions, efficacy in MASLD is predominantly contingent on metabolic reprogramming and anti-inflammatory effects

10.1073/pnas.190177497 Proc Nat Acad Sci USA

This can contribute to a clearer, healthier complexion

Astaxanthin is an antioxidant that integrates into cell membranes, where it helps protect against oxidative damage

Journal of Thoracic and Cardiovascular Surgery 167(5):P1659-1660, 2024