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For example, the redistribution of PS to the external face of the plasma membrane flags cells for their recognition, phagocytosis, 2 and ultimate degradation by phagocytes (efferocytosis)

For example, in a preclinical model of diabetes, Szymonski and collaborators showed that db/db male mice exhibit decreased glycocalyx length (assessed by atomic force microscopy) coupled with endothelial dysfunction (275)

Additionally, pathologies like cancer, diabetes mellitus, cardiovascular diseases, and chronic kidney disease can cause an increase in oxidative stress

The role of mucus on drug transport and its potential to affect therapeutic outcomes

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Devlin P., Cao X., Stanfill A.G

The role of phosphatidylserine in recognition and removal of erythrocytes