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Research: MTHFR polymorphism (C677T) reduces enzyme activity by 35% in heterozygotes and 70% in homozygotes, impairing folate metabolism and raising homocysteine

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In fact, it has been shown in rats, that quercetin alleviates BDL-induced oxidative stress, leukocyte recruitment, NF-kB activation and pro-inflammatory cytokine secretion [211]

Another mitochondrial protein that links mitochondria to the motor proteins is homolog of the Drosophila melanogaster Milton gene which is encoded by the TRAK1 (trafficking kinesin protein 1) gene

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6 Indirect antioxidants While some molecules act like antioxidants by directly scavenging free radicals, there are some bioactive compounds that can support oxidative stress balance indirectly, by regulating inflammatory pathways, redox signaling or mitochondrial function