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In vitro experiments have shown that knockdown of OTUB1 significantly impairs the migratory ability of glioma cells, and knockout of OTUB1 increases the expression of the epithelial-mesenchymal transition-related protein E-cadherin [85, 86]

After 48 h, applying nettle leaf extract at a dosage of 15 mL/L killed all of the tobacco aphids Myzus nicotianae (Shazdeahmadi, 2021)

Research has shown that ferroptosis triggers and amplifies multiple inflammatory responses, enhances inflammation by releasing damage-associated molecular patterns, further activates immune cells, and significantly stimulates the expression of inflammatory cytokines, thus forming complex connections between inflammation and ferroptosis in psoriatic skin lesions [207]

However, nanozymes generally suffer from their lower activity and unsatisfactory specificity in comparison with their natural counterparts, which severely limited their practical applications 7,8,9

Klionsky DJ, Cregg JM, Dunn WA, Emr SD, Sakai Y, Sandoval IV et al

Moreover, bEnd3 cells were subjected to Hcy treatment, both with and without the presence of THC [93]