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FIGURE 1 2.1 Orchestrating the non-immune cells in the tumor microenvironment with peptides 2.1.1 Peptide mediation in cancer-associated fibroblast-induced extracellular matrix remodeling Cancer cells recruit CAFs, which are crucial in shaping the malignant TME

[27] found that overexpression of the most abundant GPX, GPX-1, served a protective role from platelet hyperactivity and age-dependent increased susceptibility to venous thrombosis after inferior vena cava ligation in murine models

The detection of biomarkers via metabolomics analysis holds promise for personalized medicine, offering alternative adjunct therapies through gut microbiota manipulation (Chen L

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Tight junctions, which are essential for the integrity of the oBRB, were assessed by ZO1 immunofluorescence in iRPE cells

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