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Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy

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Research on thymosin beta-4 has included preclinical models and some early clinical exploration in wound healing and tissue repair

Recent research demonstrates that decreased estrogen levels enhance intestinal permeability, undermine barrier integrity, promote bacterial translocation, and increase inflammatory markers, thereby promoting the synthesis of osteoclastogenic cytokines (53, 54)