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Endocrinology 150 , 56395648 (2009)

For patients whose divalproex sodium delayed-release tablets total daily dose cannot be directly converted to divalproex sodium extended-release tablets, consideration may be given at the clinicians discretion to increase the patients divalproex sodium delayed-release tablets total daily dose to the next higher dosage before converting to the appropriate total daily dose of divalproex sodium extended-release tablets

That tissue reperfusion in animals undergoing transient focal cerebral ischemia may augment brain injury above levels observed in permanent focal cerebral ischemia is well established [72, 73]