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Hope, B
Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens
Taken together, these findings suggest that NSBSO-induced GSH depletion and synthesis inhibition can elevate intracellular ROS, thereby activating the caspase family, leading to GSDME cleavage and cell pyroptosis
The side effect profiles also differ , and some researchers switch between the two based on response and tolerance
doi: 10.1007/s11901-018-0390-1 36
Journal of Ethnopharmacology , 265 , 113195
