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doi: 10.1016/j.biocel.2007.03.010 10 ChenXYuCKangRTangD

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Feeding old rats with acetyl carnitine and lipoic acid for a few weeks restored mitochondrial function and lowered oxidants to the level of young rats [120]

Notably, canonical GPX4 inhibitors, such as RSL3 and ML162, also inhibit thioredoxin reductase 1 (TXNRD1) 121,122