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Cellular senescence is a complex process characterized by a progressive decline in organelle functionality, with mitochondrial dysfunction being a prominent hallmark

When a biopsy showed the dark lesion was, indeed, cancerous, doctors removed not only the gums but also parts of the man's upper jaw, according to the case report, published Wednesday in The New England Journal of Medicine

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The damaged nerves send chronic pain signals to the brain, while the brain, in an attempt to protect the body, may release further inflammatory signals that exacerbate the peripheral damage