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However, sufficient liver specific APOA5 gene expression was obtained in vivo with a 26 kb DNA XhoI -fragment containing only the APOA5 gene and thus lacking APOC3 enhancer [10]

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doi: 10.1126/science.1230062 124 LightbodyGHaberlandVBrowneFTaggartLZhengHParkesEet al

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Real-world data : Prospective cohorts (n=117) demonstrated sustained benefits over a median 2.0 years, with increased outdoor time (+6.1 hours/week) and improved quality of life (+14%)

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