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[DOI] [PMC free article] [PubMed] [Google Scholar] Doppalapudi S, Jain A, Khan W, Domb AJ (2020) Fenoldopam mesylate for treating psoriasis: a new indication for an old drug

Once citrate has reached the cytosol, through a citrate carrier, an integral protein of the inner mitochondrial membrane, it is cleaved to acetyl-CoA and oxaloacetate in the reaction catalyzed by citrate lyase (EC 4.1.3.6)

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96 In addition to inhibiting GPX4, FIN56 also prevents CoQ10 production by binding and activating farnesyl-diphosphate farnesyltransferase 1 (FDFT1/SQS, the squalene synthase)

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