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Although melanin pigment (mostly eumelanin) can scavenge free radicals, this is insufficient to counteract all the cutaneous consequences of ROS, as illustrated by an enhanced oxidative stress in melasma [57, 58]

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Although there is little evidence, they have encouraging results as adjunctive therapy in histamine intolerance mediated by gut

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Several other theories on how mitochondrial dysfunction may influence aging are currently being investigated

& Safarinejad, S