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Additionally, E2 regulates protein and DNA synthesis in uterine epithelial cells via the PKC/ERK/mTOR pathway, ultimately controlling cell proliferation (52)

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In particular, it has been previously shown that cysteine residues at positions 14, 47, 117, and 169 of GST are particularly susceptible to dimerization (Shen et al , 1993)

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316,317,318 Lactate-induced extracellular acidosis blocks one-carbon metabolism that short-lived effector T cells are highly dependent on, subsequently bringing about decreased histone 3 lysine 27 trimethylation (H3K27me3) deposition of memory-related genes, thereby affecting differentiation, reserving sternness and facilitating anti-tumor cytotoxicity of T cells