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Liver-related The following symptoms may indicate copper accumulation in the liver: weakness feeling tired weight loss nausea vomiting loss of appetite itching jaundice, or yellowing of the skin edema, or the swelling of legs and abdomen pain or bloating in the abdomen spider angiomas, or visible branch-like blood vessels on the skin muscle cramps Many of these symptoms, such as jaundice and edema, are the same for other conditions like liver and kidney failure

Studies conducted in vitro have demonstrated that increasing mitochondrial ATP production with MI [17,30,31] can provide protection from irregular sperm morphology while simultaneously improving motility over time and across sperm pools [198,201,202]

IGF-1R is a receptor tyrosine kinase that mediates the actions of IGF1, which binds with high affinity, whereas IGF2 and insulin bind to this receptor with low affinity [23]

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Jujuboside A is an active ingredient in Suanzaoren, and the jujubogenin obtained by its hydrolysis has the most compatible binding conformation with GABA A , with strong BBB penetration capability (Zhang F