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For instance, TMAO (1251000 M) treatment for 48 h was shown to increase apoptosis in human aortic endothelial cells (HAEC) [54]

Spiekerkoetter U, Huener G, Baykal T, Demirkol M, Duran M, Wanders R, Nezu J, Mayatepek E: Silent and symptomatic primary carnitine deficiency within the same family due to identical mutations in the organic cation/carnitine transporter OCTN2

We next sought to test whether gut microbiotaformed BB could produce TMAO in humans

It has been revealed that oxidative stress is involved in neuro-inflammation [136], cerebral injury [137, 138], and neuro-dysfunction [136,137,138], leading to neurodevelopmental disorders

This variability underscores the importance of tailored supplementation protocols

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