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CYP epoxygenases also convert the omega-3 PUFA, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), to the vasoactive and anti-inflammatory epoxy-derivatives, of which at least five regioisomers of EPA epoxides have been identified and six from DHA

Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

The GPCR arranges itself into a tertiary structure resembling a barrel, with the seven transmembrane helices forming a cavity within the plasma membrane that serves a ligand-binding domain that is often covered by EL-2
This result suggests that Tim-3 plays a protective role against liver injury by regulating macrophage activation

[DOI] [PubMed] [Google Scholar] 40.Kostandy B.B
