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doi: 10.1097/FJC.0b013e3181be7554

Statistical analysis was performed using a two-tailed Student's t -test and log-rank test

The thiol-disulfide equilibrium within the cell is known to regulate a diverse number of metabolic processes including enzyme activity, transport activity, signal transduction, and gene expression via alteration of redox sensitive transcription factors such as activator protein-1 (AP-1), nuclear factor kappa B (NFB) and p53 (Hutter et al., 1997

Clinical trials and translational research: Despite significant progress in animal models regarding ferroptosis-related studies, further validation is required before clinical application can be realized

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These convergent DEGs showed enrichment for cell adhesion- and synaptic development-related terms, suggesting that effector genes regulating neurogenesis, migration and maturation are highly interconnected across TF regulatory networks (Fig