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Furthermore, combining BPTES with chemotherapeutic drugs resensitizes drug-resistant cancer cell lines to chemotherapy, regardless of their glutamine dependence status (Masamha and LaFontaine, 2018)

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One more study indicates that upregulation of PTEN by MCR1 activation and inhibition of cyclooxygenase and prostaglandin E2 by melanotan II cause suppression of melanoma [10]

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