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J Biol Chem 284:2284022852 [DOI] [PMC free article] [PubMed] [Google Scholar] 97.Ong IZ, Kolson DL, Schindler MK (2023) Mechanisms, effects, and management of neurological complications of post-acute sequelae of Covid-19 (NC-PASC)

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This glycolytic exhaustion, intertwined with lipid toxicity, coalesces into a self-reinforcing metabolic vortex that etches both the penumbras fate and the patients long-term functional identity, directly linking metabolic collapse to neuropsychiatric sequelae like post-stroke depression and anxiety [19, 20]

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