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Notably, bisulfite-based PCR analysis highlighted that LINE-1 hypomethylation was associated with aggressive and advanced GC, suggesting its clinical value as a predictive GC-specific epigenetic biomarker [188]

A.SilinaK.CecconiV.LucchiariG.et al (2019)

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The action of nonsteroidal anti-inflammatory drugs in the digestive tract can also cause, among others, enteropathy, perforations, strictures, or lead to exacerbation or recurrence of digestive system diseases
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