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Upon optimization of a droplet digital PCR (ddPCR)-based method to ensure high sensitivity and accuracy, in one of these patients (012) the presence of donor-derived cells, amounting to 0.68% of the analyzed material, was detected (Extended Data Fig

Psychiatry 26 , 151167 (2021)

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PMID 24552327

different xenobiotics may induce distinct isoforms of the enzyme

The PLS-DA and heat map in Figure 1 show that resistant cells treated continuously with 1 M tamoxifen (4+1), a concentration that is often measured in patients (24), showed different metabolic clusters compared to the other two resistant groups (50 and 35x6) and the control (tamoxifen-sensitive) group, indicating that they had markedly different metabolic characteristics ( Figure 1A )