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Furthermore, lipid peroxidation enhances the capability of radiotherapy and chemotherapy by increasing the level of oxidative stress in cancer cells where the balance shifts toward cell death

Additionally, ROS upregulation of HIF-1 can increase angiopoietin-like 4 expression in osteoclasts and enhance osteoclast activity (228, 229)
This is the core purpose of this review

ALA has the ability to chelate metals and to scavenge free radicals

F., Ho S
