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ROS overproduction inhibits antioxidant production, leading to further oxidative damage in NAFLD (201)

(ii) large-scale silencing approaches and functional screenings, determining whether the genetic or pharmacological inhibition of specific proteins alters CDDP sensitivity (in preclinical models only) and (iii) multiplex genotyping studies, assessing in a high-throughput manner whether particular (combinations of) single-nucleotide polymorphisms (SNPs) are associated with increased or reduced CDDP sensitivity (in clinical settings)

The biochemical composition of the biomass was determined as reported in Table 1)

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Chem 73 (2001) 198A205A [PubMed] [Google Scholar] [308].Putnam DD, Wolf BF, A Burns M, Cell affinity chromatography, in: Kastner M (Ed.), Protein Liquid Chromatography, Elsevier, Amsterdam, 1999, pp