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The next day, the cells were treated with 10 M cisplatin for 3 h, fixed with 4% formaldehyde, permeabilized with 0.5% Triton X-100 and blocked with 0.5% BSA and 0.3% Triton-X-100 in PBS

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Phyton 32:109112 Salavati J, Fallah H, Niknejad Y, Barari Tari D (2021) Methyl jasmonate ameliorates lead toxicity in Oryza sativa by modulating chlorophyll metabolism, antioxidative capacity and metal translocation

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One study demonstrated that curcumin combined with paclitaxel treatment was superior to paclitaxel-placebo combination therapy in terms of ORR and physical performance after 12 weeks of treatment, and there were also no major safety concerns or reduction in quality of life (Saghatelyan et al., 2020).EGCG synergistically enhances the efficacy of drugs such as 5 - Fluorouracil and cisplatin, and reduces cardiac, renal, and other organ EGCG may synergistically enhance the efficacy of drugs such as 5-fluorouracil and cisplatin and reduce the toxicity in the heart and kidney, but some drugs (e.g., bortezomib, sunitinib) may antagonize EGCG, but clinical evidence is limited, and further validation of their safety and efficacy is needed (Lecumberri et al., 2013)

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