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All referenced applications remain strictly confined to laboratory-based investigation and non-clinical experimental use

Furthermore, evidence suggests that oxidative stress can elevate mitochondrial DNA (mtDNA) levels, thereby impacting fetal growth (Lee et al., 2000)

J Sci Food Agric 76:257262 [Google Scholar] Garg SS, Gupta J, Sharma S, Sahu D (2020) An insight into the therapeutic applications of coumarin compounds and their mechanisms of action

Abstract Introduction: Administration of high doses of acetaminophen (APAP) results in liver injury

Another study that includes patients with chronic periodontitis, detected that a overproduction of ROS by activated polymorphonuclear leukocytes in chronic inflammation may lead to premature oxidative damage of the mitochondrial DNA (mtDNA) (52)