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Description
A preclinical study demonstrated that intravenous doses of hydroxocobalamin 5 g are well tolerated by volunteer subjects
Mitochondria contain a number of NADPH generating enzymes which are required to funnel additional reductive power to antioxidant systems (Mailloux et al., 2013a)
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For example, the redox activitiy of p66Shc within mitochondria has been shown to generate H 2 O 2 in the absence of superoxide through oxidation of cytochrome c (Giorgio et al., 2005)
Oncogene 27, 65076521
