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PEGylation of interferon 2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases

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IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression

The intestinal inflammatory infiltrate consists mainly of CD4 + T cells, regulatory T cells (Tregs), and central memory T lymphocytes (Zhong et al., 2020)
