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Yes when taken responsibly, they are not only safe but also work better together

Chem Res Toxicol 19(12):16191629

One of the primary active components in this plant is gymnemic acid, which helps suppress sweetness ( When consumed prior to a sugary food or beverage, gymnemic acid blocks the sugar receptors on your taste buds ( Research shows that Gymnema sylvestre extracts can reduce the ability to taste sweetness and thus make sweet foods less appealing ( In a study in fasted individuals, half were given Gymnema extract

Emerging treatments, including FXR agonists, PPAR agonists, and novel agents targeting DNL pathways, show promise but also highlight the complexity of MASLD treatment

doi: 10.1210/me.2010-0373

This amount is to be considered an average during your diet