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Rev Neurol 2003;36:105864.

Periodontal regeneration using a xenogeneic bone substitute seeded with autologous periodontal ligament-derived mesenchymal stem cells: a 12-month quasi-randomized controlled pilot clinical trial

Remaining challenges include particle aggregation and potential toxicity, which have limited the number of polymer-based nanomedicines approved for clinical use [21]

231 found accelerated DNA methylation age in Down syndrome patients with clinical signatures of accelerated ageing. There is also evidence that frailty, a syndrome with a pronounced association with age-related phenotypes, has a significant association with DNA methylation age, but not with telomere length

Oxidative Med Cell Longev 2017:45351944535118

The normal process of aging is associated with a decrease in glutathione activity, which can result in increased oxidative activity
