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Hunner lesions can be identified on cystoscopy in men with IC/BPS
Interestingly, HGF also reduces a caspase-independent ischemic neuronal cell death by preventing apoptosis-inducing factor (AIF) translocation downstream of poly(ADP-ribose)polymerase 1 (PARP1) and p53 (Niimura et al., 2006b)
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Individual response varies depending on severity and duration of deficiency
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It may also appear to extend cellular proliferative capacity under research conditions
