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The affinity maturation of antibodies is through multiple rounds of somatic hypermutation and selection in the germinal center
This is exactly what you need for repeated withdrawal over days
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FIG 40A-G Localization of synaptic markers following Nle'-AnglV and dihexa- dependent dendritic spine induction
[PubMed] [Google Scholar] 1004
Adjusting doses based on lab trends helps prevent complications
