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3.1.5 Other mechanisms Clostridium -containing fecal microbiota transplantation (FMT) and derivatives integrate the above mechanisms to treat IBD ( CB mixtures induce lamina propria DC to produce TGF-1 via TLR2/ERK-AP-1, promoting iTreg generation and alleviating inflammation

Katsuno, T

Bavachinin, a natural compound from Fructus Psoraleae, has been shown to reduce lipid accumulation in NAFLD by promoting fatty acid oxidation and inhibiting the cholesterol synthesis enzyme Farnesyl-diphosphate farnesyltransferase 1 (FDFT1), while also enhancing cell proliferation through its facilitation of the interaction between PCNA and DNA polymerase delta

As a result, local inflammation develops, and activated immune cells and cytokines can affect other organs or trigger immune-related diseases, e.g., autoimmunity

[DOI] [PubMed] [Google Scholar] 33.Bounous G., Gold P

Identification of genes that are associated with DNA repeats in prokaryotes
