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At the cellular level, pirfenidone inhibits fibroblast activation and proliferation, including downregulation of genes related to fibroblast activation such as -SMA (Maher, 2024

We further evaluate multiple therapeutic strategies targeting ferroptosis, including iron chelators, antioxidants, GPX4 activators, and lipoxygenase inhibitors

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Given its protective mechanisms, vitamin B 6 emerges as a promising prophylactic or therapeutic agent against pathogenic infections

Amylin analogs for the treatment of obesity without diabetes: present and future

Recognizing the pathological impact of these multifaceted interactions provides a compelling rationale for therapeutically targeting this axis to reprogram anti-tumor immunitya strategy explored in the next section