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Affinity maturation of antibody R023 Cryo-EM-enabled structural characterization of R023 binding to sotorasib-conjugated p*MHCs revealed that R023 recognizes primarily the HLA and hapten moieties of its antigens, with mutational data confirming the central role of the hapten in antibody binding 33

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Low doses of insulin-like growth factor-I induce mitochondrial protection in aging rats

Obradovic M, Zafirovic S, Soskic S, Stanimirovic J, Trpkovic A, Jevremovic D, et al

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