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Two enzymes are very sensitive to oxidative modification namely glutamine synthetase and creatine kinase, which are remarkably low in AD brains, depicting the change of glutamate concentrations and increase of excitotoxicity

doi: 10.3748/wjg.v24.i30.3361 98 AntonucciLPorcuCIannucciGBalsanoCBarbaroB

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Obtaining a 3D reconstruction took considerable effort due to the highly flexible nature of the filaments (Supplementary Figs

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