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A study where GTE was administered to TAM-intoxicated rats reported significant increase in antioxidant enzymes, reduction of glutathione concomitant, and significant decrease in the levels of thiobarbituric acid reactive substance (TBARS) and liver transaminase ( Rats treated with TAM showed elevated aminotransaminase, carbonyl groups (CGs), and 8-hydroxydeoxyguanosine (8OHdG) ( Dimethyl-4.4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2.2'-dicarboxylate (DDB), a structural analog of Schizandrin B and Schizandrin C, is one of many compounds isolated from Chinese herbal medicine Schisandra chinensis (Turcz.) Baill
Teegen et al., 2009), cholangitis (Muratori et al., 2001), and many other chronic diseases

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It has been assumed that the patients may already have low-affinity antibodies for platelet glycoprotein

& Mendoza, C