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Here the authors show that i) kidney function is the main determinant of serum TMAO, ii) TMAO increases kidney scarring with TGF-1 signalling and iii) anti-diabetic drugs with reno-protective properties such as GLP1R agonists reduce plasma TMAO.

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The heterogeneous nature of this chronic inflammatory disease poses challenges during its treatment

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Alpha-Lipoic Acid (R-ALA) is a potent antioxidant that protects your cells from oxidative stress and improves cellular energy