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The anticipated significant increases in cerebrocortical and pituitary 5DII activities in response to hypothyroidism, as well as thyroid GPx an 5DI and pituitar 5DI activities, are mostly unaffected by selenium deficiency in rats

As evidenced by the pioneering work of Hwang et al., using a small, radiolabeled peptide, susceptible to oxidation, the GSH/GSSG ratio in ER is remarkably low, ranging from 1:1 to 3:1

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