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For IBS, leaky gut, or inflammatory bowel conditions, the oral or sublingual troche is the first-choice route

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doi: 10.1164/art.1943.47.6.549 106 KandelN.ZhengT.HuoQ.TatulianS

Glucocorticoid therapeutic administration in pathological conditions, such as atherosclerosis, restenosis, chronic graft rejection, and ischemia appears to be beneficial as glucocorticoids inhibit the remodeling processes that lead to lesions by regulating the inflammation, angiogenesis, and cardiomyocyte apoptosis [68,69]