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PMID: 37432180

Probiotics Probiotics are live microorganisms that can enhance gut health and reduce inflammation [81]
Sirtuin 1 (SIRT1) negatively regulates GH-induced IGF-1 production in the liver by directly inhibiting signal transducer and activator of transcription 5 (STAT5) activation, which causes GH resistance under prolonged fasting, starvation, and malnutrition [6]

Translational Medicine 15 (1), 197

40 Orhan KiliB.KiliS.ahin EroluE.GlE.Belen ApakF

This convergent signaling produces amplified responses
