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It is noteworthy that even fluctuations in ALT levels within the upper limits of the normal reference range may indicate subclinical hepatic dysfunction [48]

[DOI] [PMC free article] [PubMed] [Google Scholar] 179.Etyang AO, Khayeka-Wandabwa C, Kapesa S, Muthumbi E, Odipo E, Wamukoya M, Ngomi N, Haregu T, Kyobutungi C, Tendwa M, Makale J, Macharia A, Cruickshank JK, Smeeth L, Scott JA, Williams TN

doi: 10.1210/er.2001-0034 87 Chiu-UgaldeJWirthEKKleinMOSapinRFradejas-VillarNRenkoKet al

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AMPK, in turn, is the key sensor of ATP deficiency, specifically a shift in the AMP/ADP/ATP ratio toward AMP