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(6) There are analyses indicating that more than half of all arthroplasty patients are obese, with one large retrospective cohort of 8.3 million individuals reporting that 64% of primary total knee arthroplasty (TKA) patients and 49% of primary total hip arthroplasty (THA) patients are obese

DHAR also plays an important role in abiotic stress tolerance and its expression is activated by a number of abiotic stress factors (Ali et al., 2008

Early warning signs include persistent fatigue that does not improve with rest, difficulty concentrating or brain fog, tingling or numbness in hands and feet, weakness in the legs, dizziness when standing up, pale or yellowish skin, and a sore or swollen tongue

Reactive oxygen species (ROS): plant perspectives on oxidative signalling and biotic stress response

Countless studies have shown that if glutathione is not in the right form, and the correct molecular structure, it oxidizes and breaks down before it ever even has a chance to absorb

Besides, nutraceuticals, including acety-L-carnitine, glutamine, vitamin E and A-Lipoic acid, have also been applied for CIPN intervention but achieved little positive clinical outcomes (Table 2 ) [126]