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Lai CS, Piette LH

Results Cohort characteristics This is a single-centered cohort and consisted of 60 PCR-confirmed SARS-CoV-2 infected individuals (30 LC patients, 15 individuals without LC symptoms who were previously infected with SARS-CoV-2 but recovered without any symptoms per se (recovered group, denoted R), 15 acute hospitalized COVID-19 patients (A)) as well as 15 healthy controls (HCs) without acute symptoms and negative SARS-CoV-2 immunoassays ( Figure 1A , Supplementary Table 1 )

The release of free cobalamin from the lysosome requires the action of the lysosomal membrane protein identified as LMBRD1 (LMBR1 domain containing 1, where LMBR1 refers to the protein identified as limb region 1 protein homolog)

[DOI] [PubMed] [Google Scholar] 59.Harman D

Khor TO, Huang M-T, Prawan A, Liu Y, Hao X, Yu S, et al

We further demonstrated that the decrease in brain TLR-4 following NAC administration was associated with an increase in brain antioxidant glutathione levels, potentially enabling the brain to cope with increased oxidative stress and thus to amelioate brain injury