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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.van Asbeck BS, Hoidal J, Vercellotti GM, et al

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The LD 50 (lethal dose, the dose which kills 50% of the injected fish) was assessed before the final challenge up to 10 days by following Reed and Muench (1938)

Circulation 13 , 7480 (2006)

Serum B12, and potentially methylmalonic acid (MMA) and homocysteine, give your clinician the data to determine whether B12 is a contributing factor or whether the mood symptoms are being driven by something else entirely