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PMID: 20554713

Like most treatments, vitamin B12 injections carry warnings that patients should be aware of, including: Hereditary Optic Nerve Atrophy: People with early Lebers disease (a hereditary form of optic nerve atrophy) should not receive cyanocobalamin injections, as rapid and severe vision loss has occurred

Compounding pharmacies which were barred from producing injectable GHK-Cu since 2023 can now begin preparing pharmaceutical-grade product again (effective July 2026 once advisory panel guidance is finalized)

However, knocking down CD38 expression with siRNA did not affect macrophage polarization or T-cell activation

If a severe allergic reaction does occur, it will usually be within 20 - 30 minutes of giving the injection and the most common sign is collapse